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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK2
All Species:
17.58
Human Site:
T42
Identified Species:
35.15
UniProt:
P49760
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49760
NP_003984.2
499
60090
T42
W
S
S
S
S
D
R
T
R
R
R
R
R
E
D
Chimpanzee
Pan troglodytes
XP_513855
498
59985
T42
W
S
S
S
S
D
R
T
R
R
R
R
R
E
D
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
R183
R
E
H
E
G
R
L
R
Y
P
S
R
R
E
P
Dog
Lupus familis
XP_547549
536
63798
T78
W
S
S
S
S
D
R
T
R
R
R
R
R
E
D
Cat
Felis silvestris
Mouse
Mus musculus
O35491
499
59936
T42
W
S
S
S
S
D
R
T
R
R
R
R
R
E
D
Rat
Rattus norvegicus
Q63117
490
58467
P42
R
Y
P
S
R
R
E
P
P
P
R
R
S
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIU3
526
59419
S42
G
L
T
T
L
G
K
S
G
L
P
V
V
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
R66
D
T
G
Y
A
R
S
R
S
Y
D
N
R
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Q358
V
K
Y
Q
Q
Q
Q
Q
H
P
H
T
Q
F
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTF3
817
89866
S340
G
G
P
N
K
H
L
S
A
S
H
S
T
L
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
W26
R
K
R
A
R
L
G
W
D
V
L
P
Q
A
T
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
S192
S
L
P
Q
L
P
L
S
K
L
S
Y
Q
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
51.2
91.5
N.A.
96.7
59.9
N.A.
N.A.
21.2
N.A.
74.9
N.A.
37
N.A.
20.4
N.A.
Protein Similarity:
100
99.8
62.3
91.7
N.A.
98.1
73.7
N.A.
N.A.
39.7
N.A.
83.8
N.A.
48.4
N.A.
34.5
N.A.
P-Site Identity:
100
100
20
100
N.A.
100
20
N.A.
N.A.
6.6
N.A.
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
N.A.
40
N.A.
20
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
34
0
0
9
0
9
0
0
0
42
% D
% Glu:
0
9
0
9
0
0
9
0
0
0
0
0
0
42
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
17
9
9
0
9
9
9
0
9
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
9
0
0
9
0
17
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
9
0
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
17
0
0
17
9
25
0
0
17
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
17
% N
% Pro:
0
0
25
0
0
9
0
9
9
25
9
9
0
0
9
% P
% Gln:
0
0
0
17
9
9
9
9
0
0
0
0
25
9
9
% Q
% Arg:
25
0
9
0
17
25
34
17
34
34
42
50
50
9
0
% R
% Ser:
9
34
34
42
34
0
9
25
9
9
17
9
9
17
17
% S
% Thr:
0
9
9
9
0
0
0
34
0
0
0
9
9
0
9
% T
% Val:
9
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% V
% Trp:
34
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
9
0
0
0
0
9
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _